On request here is how to set the profile option value using PL/SQL
Function FND_PROFILE.SAVE can be used to set the value of any profile option at any level i.e. Site, Application, Responsibility, User etc.
Below is a sample code of how to use this function
DECLARE
a BOOLEAN;
BEGIN
a :=
fnd_profile.SAVE ('CONC_REPORT_ACCESS_LEVEL',
'R',
'USER',
'22746',
NULL,
NULL);
IF a
THEN
DBMS_OUTPUT.put_line ('Success');
COMMIT;
ELSE
DBMS_OUTPUT.put_line ('Error');
END IF;
END;
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